What is the best handgun cartridge and bullet design for you to carry on the street?
My standard response to this question is to carry the largest caliber, with the heaviest bullet, loaded as hot as you can handle it in order to deliver two, quick center of mass shots… and have the skills to be able to follow up with a precise shot to the cranio-ocular cavity (between the eyebrows and moustache) when the first two thoracic cavity hits don’t stop an extremely dedicated opponent.
